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  4. This is why so many people believe in ghosts, spirits and the paranormal

This is why so many people believe in ghosts, spirits and the paranormal

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  • I Offline
    I Offline
    ILisa
    wrote on last edited by
    #14

    http//www.bbc.co.uk/science/horizon/2002/homeopathytrans.shtml

    There. Disproven.

    PROVEN! *warning this is a LONG passage!!

    Homeopathy research and surveys, ENHR, January 2005

    Meta-analysis

    Jonas, W. B., Kaptchuk, T. J., & Linde, K. 2003b, "A critical overview of homeopathy",
    Ann.Intern.Med., vol. 138, no. 5, pp. 393-399.
    Cucherat, M., Haugh, M. C., Gooch, M., & Boissel, J. P. 2000, "Evidence of clinical efficacy of
    homeopathy. A meta-analysis of clinical trials. HMRAG. Homeopathic Medicines Research Advisory
    Group", Eur.J.Clin.Pharmacol., vol.. 56, no. 1, pp. 27-33.
    Homeopathy research and surveys, ENHR, January 2005 Page 4 of 12

    META-ANALYSES SHOWING THAT HOMEOPATHY WORKS
    A systematic review of results from 93 substantive RCTs was carried out by robert Mathie (2003). It
    concludes that of the 35 different medical conditions covered by these trials the weight of evidence
    favours a positive treatment effect in 8 childhood diarrhoea, fibrositosis, hayfever, influenza, pain
    (miscellaneous), side-effects of chemotherapy or radiotherapy, sprains and upper-respiratory tract
    infections.
    Mathie, R. The research evidence base for homeopathy a fresh assessment of the literature.
    Homeopathy 92 84-91. 2003.

    Meta analysis of 89 trials on homeopathic medicine versus placebo.
    Result significanly in favour of homeopathy (OR 2,45 (95% CI 2,05-2,93)).

    This meta-analysis included 186 placebo-controlled
    studies of homeopathy published until mid-1996, of which data for analysis could be extracted from
    89. The overall odds ratio was 2.45 (95% confidence intervals 2.05-2.93) in favour of homeopathy,
    which means that the chances that homeopathy would benefit the patient were 2.45 times greater than
    placebo. When considering just those trials of high quality published in MEDLINE listed journals, and
    with predefined primary outcome measures, the pooled odds ratio was 1.97 and significant. Even after
    correction for publication bias the results remained significant. The main conclusion was that the
    results "were not compatible with the hypothesis that the effects of homeopathy are completely due to
    placebo". If the result of new trials were to show no difference between homeopathy and placebo, we
    would have to add 923 trials with no effect with 118 patients in each in order to balance the two.
    Linde K, Clausius N, Ramirez G, et al. Are the clinical effects of homoeopathy placebo effects? A
    meta-analysis of placebo-controlled trials. Lancet 1997;350834-43.

    HMRG report with overview of clinical research in homeopathy, identified 184 controlled clinical
    trials. They selected the highest quality randomized control trials, which included a total of 2617
    patients for a meta-analysis. This meta-analysis resulted in a p-value of 0.000036 indicating that
    homeopathy is more effective than placebo. The researchers concluded that the "hypothesis that
    homeopathy has no effect can be rejected with certainty". Homeopathic Medicine Research Group.
    Report to the European Commission directorate general XII science, research and development. Vol
    1 (short version). Brussels European Commission, 199616-7.

    Of the 105 trials with interpretable results, 81 trials indicated positive results. Most studies showed
    results in favour of homeopathy even among those randomized controlled trials that received highquality
    ratings for randomization, blinding, sample size, and other methodological criteria. They came
    to the following conclusion "The amount of positive evidence even among the best studies came as a
    surprise to us. Based on this evidence we would readily accept that homeopathy can be efficacious, if
    only the mechanism of action were more plausible. The evidence presented in this review would
    probably be sufficient for establishing homeopathy as a regular treatment for certain indications".
    Kleijnen J, Knipschild P, Ter Riet G. Clinical trials of homoeopathy. British Medical Journal.
    1991b;302316-23.

    Meta-analysis of 105 articles on laboratory research.
    Result positive effect 50% more frequently than
    negative effect among trials of highest methodological quality. (1994)
    Linde K. Jonas WB, Melchart D, Worku F, Wagner H, Eital F. Critical Review and Meta-Analysis of
    Serial Agitated Dilutions in Experimental Toxicology. Human and Experimental Toxicology.
    1994;13481-492.

    A meta-analysis of three trials on homeopathic immunotherapy. Result significant effect in favour of
    homeopathic treatment.

    Reilly D, Taylor MA, Beattie NGM, Campbell JH, McSharry C, Aitchison TC, Carter R, Stevenson
    RD. Is evidence for homoeopathy reproducible? Lancet. 1994;3441601-1606.
    Homeopathy research and surveys, ENHR, January 2005 Page 5 of 12

    KEY CLINICAL TRIALS IN HOMEOPATHY
    Diarrhoea in children
    Treatment of acute childhood diarrhoea in Nicaragua
    This trial involved 81 children aged from 6 months to 5 years in a randomised, double-blind trial of
    intravenous fluids plus placebo versus intravenous fluids plus homeopathic remedy individualised to
    the patient. The treatment group had a statistically significant decrease in duration of diarrhoea.
    Jacobs J. Treatment of acute childhood diarrhea with homeopathic medicine a randomized clinical
    trial in Nicaragua. Pediatrics 1994; 93 719-725.
    Treatment of acute childhood diarrhouea, repeated in Nepal
    In a replication of a trial carried out in Nicaragua in 1994, 116 Nepalese children aged 6 months to 5
    years suffering from diarrhoea were given an individualised homoeopathic medicine or placebo.
    Treatment by homoeopathy showed a significant improvement in the condition in comparison to
    placebo.
    Jacobs J., Jimenez M., Malthouse S., Chapman E., Crothers D., Masuk M., Jonas W.B., Acute
    Childhood Diarrhoea- A Replication., Journal of Alternative and Complementary Medicine, 6, 2000,
    131-139.
    A meta-analysis of childhood diarrhoea trials
    This meta analysis of 242 children showed a highly significant result in the duration of childhood
    diarrhea (P=0.00. It should be noted that the World Health Organisation consider childhood diarrhea
    to be the number one public health problem today because of the millions of children who die every
    year from dehydration from diarrhea.
    J. Jacobs, WB Jonas, M Jimenez-Perez, D Crothers, Homeopathy for Childhood Diarrhea Combined
    Results and Meta-analysis from Three Randomized, Controlled Clinical Trials
    http//homeopathic.com/articles/research/diarrhea_t.php

    Respiratory tract complaints
    Homeopathy versus conventional treatment in respiratory tract complaints
    In an outcome study, 30 practitioners in four countries enrolled 500 consecutive patients with at least
    one of three complaints upper respiratory tract complaints including allergies; lower respiratory tract
    complaints including allergies; or ear complaints. Of 456 patients, 281 received homeopathy and 175
    conventional treatment. The primary outcomes criterion was response to treatment, defined as cured or
    major improvement after 14 days of treatment. Results showed a response rate of 82.6% in the
    homeopathy group compared to 67.3% in the group receiving conventional medicine. The authors
    concluded that homeopathy appeared to be at least as effective as conventional treatment of patients
    with the three conditions studied.
    Riley D, Fischer M, Singh B, Haidvogl M, Heger M. Homeopathy and conventional medicine an
    outcomes study comparingeffectiveness in a primary care setting. J Altern Complement Med 2001; 7
    149?159.

    Homeopathy versus conventional treatment in otitis media
    Prospective observational study, comparision of homeopathy versus conventional treatment in acute
    otitis media. Conclusion homeopathy should be first line treatment in acute otitis media. Results
    showed median duration of pain of 2 days in the homeopathy-group and 3 days in the conventional
    medicine group. 70.7 % of the children receiving homeopathic treatment did not have another ear
    infection the next year and 29.3 % had a maximum of three ear infections within one year. 56.5 % in
    the conventional medicin group did not have another ear infection the next year and 43.5 % had a
    maximum of six ear infections the next year. Results showed that in the group receiving homeopathic
    treatment only 5 out of 103 children needed antibiotics.
    Friese K-H, Kruse S, Ludtke R, Moeller H "Homeopathic treatment of otitis media in children
    comparisons with conventional therapy". Int J Clin Pharmacol Ther. 1997; 35 296-301.
    Homeopathy research and surveys, ENHR, January 2005 Page 6 of 12
    Acute otitis media in children
    A study involving children suffering from acute otitis media suggests that a positive treatment effect
    from homeopathy when compared with placebo in acute otitis media cannot be excluded. There were
    fewer treatment failures in the group receiving homeopathy after 5 days, 2 weeks, and 6 weeks, with
    differences of 11.4, 18.4, and 19.9%, respectively, but these differences were not statistically
    significant. Diary scores showed a significant decrease in symptoms at 24 and 64 h after treatment in
    favour of homeopathy (P<0.05). The authors concluded that these results suggest that a positive
    treatment effect of homeopathy when compared with placebo in acute otitis media cannot be excluded
    and that a larger study is justified.
    Jacobs J, Springer DA, Crothers D. Homeopathic treatment of acute otitis media in children a
    preliminary randomized placebo-controlled trial. Pediatr Infect Dis J 2001; 20 177?183.
    Acute otitis media in children
    In a trial of 230 children who were given homeopathic treatment to treat acute otitis media, pain
    control was achieved in 39% of the patients after 6 h and another 33% after 12 h. The resolution rates
    were 2.4 times faster than in placebo controls. No complications were observed and compared to
    conventional treatment the homeopathic approach was 14% cheaper.
    Frei H, Thurneysen A. Homeopathy in acute otitis media in children treatment effect or spontaneous
    resolution? Br Homeopath J 2001; 90 180?182.

    Glue ear in children
    In a pilot study in children suffering from glue ear treated with homeopathy 75% had normal
    tympanogram, compared to 31% in the group treated with conventional medicine. A higher proportion
    of children receiving home opathic treatment had a hearingloss less than 20 dB at follow-up, though
    the difference was not statistically significant. The authors concluded that further research comparing
    home opathy to standard care is warranted; 270 patients would be needed for a definitive trial.
    Harrison H, Fixsen A, Vickers A. A randomized comparison of homoeopathic, standard care for the
    treatment of glue ear in children. Compl Therap Med 1999; 7 132?135.

    Acute sinusitis
    In a trial of 119 patients suffering from clinical signs of acute sinusitis were treated using homeopathic
    medicines. Typical sinusitis symptoms, such as headache, pressure pain at nerve exit points, and
    irritating cough, were reduced after a mean of 4.1 days of treatment. Ninety-nine received only a test
    medication, 20 patients were able to discontinue concomitant medication at the first visit, and only one
    patient needed antibiotics. Average duration of treatment was 2 weeks. At the end of treatment 81.5%
    described themselves as symptom free or significantly improved. No adverse drugeffects were
    reported.

    Adler M. Efficacy, safety of a fixed-combination homeopathic therapy for sinusitis. Adv Ther 1999;
    16 103?111.

    Homeopathy research and surveys, ENHR, January 2005 Page 7 of 12

    KEY CLINICAL TRIALS IN HOMEOPATHY
    Musculo-sceletal problems
    Rheumatoid arthritis
    Forty-six patients with rheumatoid arthritis received an individualised remedy or placebo in a 3-month
    randomised trial. Both groups were allowed to continue standard anti-inflammatory drugs. After 3
    months, the double-blind code was broken and remedies were given to members of the placebo group
    in a single crossover study. Articular index, limbering up time, grip strength and pain all showed
    statistically significant differences.
    Gibson RG, Gibson SLM, MacNeill AD, Buchanan WW Homeopathic therapy in rheumatoid arthritis
    evaluation by double-blind clinical therapeutic trial. British Journal of Clinical Pharmacology 1980;
    9 453-459.

    Osteoarthritis
    In this trial, 65 sufferers of Osteoarthritis (OA) were split into 2 groups, and through a double blinding
    process were given either a homoeopathic medicine or Acetaminophen, a commonly prescribed drug
    for pain relief in OA. Researchers found that homoeopathy provided a level of pain relief that was
    superior to Acetaminophen, and produced no adverse reactions.
    Shealy C.N., Thomlinson P.R., Cox R.H., and Bormeyer V. Osteoarthritis Pain A Comparison of
    Homoeopathy and Acetaminophen. American Journal of Pain Management, 8, 3, July 1998, 89-91.

    Fibromyalgia
    A double-blind, randomised, placebo-controlled trial of individualised homeopathic treatment (LM
    potency) versus placebo concluided that idividualised homeopathy is significantly better than placebo
    in lessening tender point pain and improving the quality of life and global health of persons with
    fibromyalgia.
    Bell IR, Lewis II DA, Brooks AJ, Schwartz GE, Lewis SE, Walsh BT, Baldwin CM. Improved clinical
    status in fibromyalgia patients treated with individualized homeopathic remedies versus placebo
    http//rheumatology.oupjournals.org/cgi/reprint/keh111.

    Fibrositis
    In a randomised placebo-controlled trial of patients with fibrositis, only those patients in whom Rhus
    toxicodendron was ?unequivocally indicated? were admitted to the study. After 1 month?s treatment,
    the were highly significant improvements in objective and subjective parameters.
    Fisher P. An experimental double-blind clinical trial in homoeopathy. British Homoeopathic Journal
    1986; 75 142-147.
    Homeopathy research and surveys, ENHR, January 2005 Page 8 of 12

    KEY CLINICAL TRIALS IN HOMEOPATHY
    Hayfever, asthma and perennial rhinitis
    Reilly and colleagues have conducted a series of trials in patients with hayfever, asthma and perennial
    rhinitis. Patients were given skin tests and remedies were chosen on the basis of reactivity. This design
    allows individualisation whilst avoiding the issues of case-taking and the effect that this has on the
    process. The results demonstrate a significant difference between the placebo and homeopathic groups
    which is reproducible. ?The results suggest that either homeopathy works, or, that the clinical trial
    does not.? (Anon, 1994). (NB! Strictly speaking these are trials of isopathy.)
    Anon. Reilly?s challenge (editorial). Lancet 1994; 344 1585.
    Reilly DT, Taylor MA. Potent placebo of potency? A proposed study model with initial findings using
    homoeopathically prepared pollens in hay fever as a model. British Homoeopathic Journal 1985 ; 74
    65-75.
    Reilly DT, Taylor MA, Campbell J, Beattie N, McSharry C, Aitchison T, Carter R, Stevenson R. Is
    evidence for homoeopathy reproducible? Lancet 1994; 334 1601-1606.
    Reilly DT, Taylor MA, McSharry C, Aitchison T. Is homoeopathy a placebo response? Controlled trial
    of homoeopathic potency, with pollen in hay fever as a model. Lancet 1986; ii 881-886.
    Taylor MA, Reilly D, Llewellyn-Jones RH, McSharry C, Aitchison T, Lancaster T, Vickers A.
    Randomised controlled trial of homeopathy versus placebo in perennial allergic rhinitis with overview
    of four trial series British Medical Journal 2000; 321 471-476.

    Female complaints

    Polycystic Ovary Syndrome

    36 women suffering from Polycystic Ovary Syndrome (PCOS), and fitting the mental picture of the
    homoeopathic remedy Pulsatilla, were given Pulsatilla 6C, 4 hourly throughout the day for 2 weeks
    after the end of menstruation, and this was repeated for 4 consecutive cycles. At the end of the trial 30
    of the 36 women had complete disappearance of the symptoms of PCOS and the production of normal
    ovulating follicles and a further 4 of the 36 became asymptomatic.
    Sanchez-Resendiz J., Guzman-Gomez F., Polycystic Ovary Syndrome. Boletin Mexicano de
    Homeopatica, 30, 1997, 11-15.

    Pre menstrual syndrome (PMS)

    In a randomized controlled double-blind clinical trial (1992-94) 19 women suffering from PMS were
    treated with individually with homeopathy. 90 % of the patients who had receieved homeopathic
    treatment experienced more than 30 % improvement. Only 37.5 % of patients who received placebo
    experienced a similar improvement. Sick-days before menses were reduced from 0.75 to 0 in the
    homeopathy-group, and was unchanged in the control group. Use of conventional drugs was also
    reduced in the homeopathy-group.
    Yakir M, Kreitler S, Brzezinski A, Vithoulkas G, Oberbaum M, Bentwich Z.

    Effects of homeopathic treatment in women with premenstrual syndrome a pilot study. Br Homeopath J.
    2001 Jul ;90(3) 148-53.

    Homeopathy and oestrogen withdrawal

    40 out of 45 women with breast cancer withdrawing from oestrogen and then treated homeopathically,
    experienced significant improvement in their primary symptoms, anxiety and depression, as well as
    improvement in quality of life. Primary symptoms changed from 7.8 to 5.4, and from 7.2 to 4.1
    (p<0.001). The homeopathic approach appears to be clinically useful in the management of oestrogen
    withdrawal symptoms in women with breast cancer.
    Thompson EA, Reilly D. The homeopathic approach to the treatment of symptoms of oestrogen
    withdrawal in breast cancer patients. A prospective observational study.
    Homeopathy. 2003 Jul;92(3)131-4.
    Homeopathy research and surveys, ENHR, January 2005 Page 9 of 12

    Homeopathy in menopausal complaints
    In a prospective study 82 % of 102 patients reported improvement of menopause symptoms after
    homeopathic treatment. Main symptoms noted were hot flushes and sweats, tiredness, anxiety,
    sleeping difficulties, mood swings and headaches. Women referred to homeopathy were those who
    either could not take hormone related treatment (HRT), for whom HRT was unsuccessful, who did not
    want or who had to come off HRT. Mean length of homeopathic treatment was 5 months.
    Relton, C. NHS Homeopathy Menopause Service. Outcome Study. In press.

    Other noteable trials
    ME
    A randomised double-blind trial involving 62 patients with ME, reported in some detail, found that
    33% of patients in the group receiving homeopathic remedies showed definite improvement compared
    with none in the placebo group.
    Awdry R. Journal of Alternative and Complementary Medicine 1996; February, March, April.

    Dengue haemorrhagic fever

    Dengueinum 30 was administered to at least 39,200 people in the Delhi area during an epidemic of
    Dengue haemorrhagic fever. Follow-up of 23,520 people 10 days later showed only 5 people (0.125%)
    had developed mild symptoms, with the rest showing no signs or symptoms of the disease.
    Central Council of Research in Homoeopathy. CCRH News 1996-1997.
    Cost benefit
    In a survey of 223 patients in a NHS General Practice, the number of consultations with general
    practitioners were reduced by 70% in a 1 year period. Expenses for medication were reduced by 50%
    when homeopathic treatment was made available.81

    Christie EA, Ward AT. Report on NHS practice-based homoeopathy project. Analysis of effectiveness
    and cost of homoeopathic treatment within ad GP practice at St. Margaret?s Surgery, Bradford on
    Avon, Wilts. September 1996. The Society of Homeopaths. ISBH 1 901262 006.

    In a study of 351 adults suffering from allergies, 35.3% received homeopathic treatment, the
    researchers concluded that alternative medicine is used widely for allergies by the general population
    and is associated with considerable costs. This has implications for the healthcare system and health
    policy. The study also showed that alternative medicine users were better educated than non-users, and
    assessed the results of alternative medicine as very good (28.6%) or rather good (53.8%).
    Schafer T, Riehle A, Wichmann HE, RingJ. Alternative medicine in allergies?prevalence, patterns of
    use, and costs. Allergy 2002; 57 694?700.

    A study of the cost and effectiveness of homeopathy suggested that doctors practising homeopathy
    issue fewer prescriptions and at a lower cost than their colleagues. The main costs for homeopathic
    treatment are for consultations with each individual patient. Costs for the actual medications used are
    relatively low, particularly when compared with conventional drugs.

    Swayne J. The cost, effectiveness of homoeopathy. A pilot study, proposals for future research. Br
    Homoeopath J 1992; 81 148?150.
    Homeopathy research and surveys, ENHR, January 2005 Page 10 of 12

    Basic research

    The effect of high dilutions
    In a multi-centre study including four research centres in Europe the effect of high dilutions of
    histamine (10-30 ? 10-38 M) were confirmed. Researchers were able to document that high dilutions of
    histamin inhibit human basophil degranulation. Results cannot be explained through molexular
    theories.
    Belon P, Cumps J, Ennis M, Mannaioni PF, Roberfroid M, Sainte-Laudy J, Wiegant FAC. Histamine
    dilutions modulate basophil activation. Inflamm. Res. 2004; 53 181-188.
    The effect of high dilutions was documented in an experiement showing the effect of highly diluted
    Belladonna on acetylcholine-induced contraction of the rat ileum. The model is reproducible and
    highly recognised in ?the scientific world?.
    Bastide M (ed). Signals and Images. Kluwer Academic Publishers 1997 161-170
    Information to be included
    Lorenz, I., Schneider, E. M., Stolz, P., Brack, A., & Strube, J. 2003, "Sensitive flow cytometric method
    to test basophil activation influenced by homeopathic histamine dilutions", Forsch Komplementarmed
    Klass Naturheilkd, vol. 10, no. 6, pp. 316-324.

    Treatment of animals
    In a blinded study where rats were treated for urinary infections results showed that rats treated with
    homeopathic remedies had clear reduction of bacterial colonies. Results were at least as clear as for
    treatment with antibiotics. Untreated rats had no changes in bacteria colonies, compared to a reduction
    to 33 % of original bacteria levels in rats treated with antibiotics, and 22 % and 39 % in rats treated
    with homeopathic remedies (Phosphorus and self-nosode).
    Gon?alves et al. O uso da homeopatia no tratamento da infec??o urin?ria em ratas. Anais do VIII
    SINAPIH; 20-22 May, 2004 p.25-26.

    A study of homeopathically protentised remedies showed a reduction in the need for repetition of
    insemination and semen loss in treatment of fertilisation of female pigs.
    Riaucourt A. L?Exemple de la Fili?re Porcine. Annals of the ?Entretiens Internationaux de Monaco
    2002?, 5-6 October, 2002.

    In a study of homeopathically potentised remedies the incidence of haematomas was reduced by 30 %
    in turkeys during transportation. The study was randomised, placebo controlled and double blinded.
    Filliat C. Particularit? de l?utilisation de l?hom?opathie en production avicole. Annals of the
    ?Entretiens Internationaux de Monaco 2002?, 5-6 October 2002.
    Homeopathy research and surveys, ENHR, January 2005 Page 11 of 12

    RESEARCH WEBSITE ADDRESSES

    Pubmed (National Library of Medicine) www.ncbi.nlm.nih.gov/entrez/query.fcgi
    British Medical Journal http//bmj.bmjjournals.com (search for 'homeopathy&#039
    New Scientist http//www.newscientist.com (search for 'homeopathy&#039
    Healthworld Online (Medline, Medical Research & Document Delivery)
    http//www4.infotrieve.com/newmedline/summary.asp
    Biomail http//www.biomail.org This site offers free regular updates by e-mail. Hosted by Medical Informatics
    Department at State University of New Yeork, Stony Brook University Hospital and Medical Center.
    An evidence-based resource about Complementary and Alternative Medicine www.cam.org.nz
    Funded by the New Zealand Ministry of Health.
    Annals of Internal Medicine http//www.annals.org/cgi/search?fulltext=homeopathy
    University of York http//www.york.ac.uk/inst/crd/ehc73.pdf
    Biomed Central (homeopathy review) http//www.biomedcentral.com/1472-6882/1/12
    British Homeopathic Library http//www.hom-inform.org
    The Research Council for Complementary Medicine www.rccm.org.uk
    Groupe International de Recherche sur l'Infinit?simal www.giriweb.com
    National Centre for Complementary and Alternative Medicine
    http//www.campain.umm.edu/ris/risweb.isa (search for 'homeopathy&#039
    National Centre for Homeopathy http//www.homeopathic.org/research.htm
    Homeopathic Educational Services http//www.homeopathic.com/articles/research/index.php
    Homeopathy (the journal) http//www.harcourt-international.com/journals/homp
    Boiron http//www.boiron.com/en/htm/04-politique/clinique.htm
    Official Indian research centre http//www.ccrhindia.org
    Carstens stiftung (Germany)
    http//www.carstens-stiftung.de
    http//www.carstens-stiftung.de/eng/index.shtml (English pages)
    ISI Web of Knowledge (resembles PubMed but includes more areas)
    http//isi3.isiknowledge.com/portal.cgi
    BMC Complementary and Alternative Medicine (free articles)
    http//www.biomedcentral.com/1472-6882
    French page with links to most published articles.
    http//dumenat.smbh.univ-paris13.fr/univer-site-homeo/francais/archmed2002.htm
    NAFKAM, Troms? (Norway) (research info will be included) http//uit.no/nafkam/omnafkam
    Vifab (Denmark) http//www.vifab.dk
    Townsend Letter for Doctors & Patients publishes a print alternative medicine magazine.
    http//www.townsendletter.com
    Homeopathy research and surveys, ENHR, January 2005 Page 12 of 12

    Comments and corrections to the ENHR report on ?Homeopathy research and surveys?
    January 2005


    1 Reply Last reply
    0
    • U Offline
      U Offline
      unknownuser
      wrote on last edited by
      #15

      I'm not going to go through a novel's worth of referencs, but anyway (these are not hand-picked, I just searched and clicked the first one each time)

      http//www.annals.org/cgi/reprint/138/5/393.pdf - Most clinical trials are poor. Most report no effect over placebos. Some report positive effects - but "further rigorous research is needed".

      http//www.biomedcentral.com/1472-6882/2/4 - 40% effectiveness

      http//www.ncbi.nlm.nih.gov/sites/entrez?db=PubMed&cmd=retrieve&dopt=abstract&list_uids=10853874 - "CONCLUSIONS There is some evidence that homeopathic treatments are more effective than placebo; however, the strength of this evidence is low because of the low methodological quality of the trials. Studies of high methodological quality were more likely to be negative than the lower quality studies. Further high quality studies are needed to confirm these results."

      http//www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&amp=&amp=&amp=&db=PubMed&list_uids=10796532&dopt=Abstract - "REVIEWER'S CONCLUSIONS There is not enough evidence to reliably assess the possible role of homeopathy in asthma. As well as randomised trials, there is a need for observational data to document the different methods of homeopathic prescribing and how patients respond."

      Here's a good one http//pediatrics.aappublications.org/cgi/content/abstract/93/5/719 - Treatment of Acute Childhood Diarrhea With Homeopathic Medicine A Randomized Clinical Trial in Nicaragua - Conclusions. The statistically significant decrease in the duration of diarrhea in the treatment group suggests that homeopathic treatment might be useful in acute childhood diarrhea. Further study of this treatment deserves consideration.

      http//www.blackwell-synergy.com/links/doi/10.1046/j.1365-2125.2002.01699.x/full/?cookieSet=1 - "Collectively these data do not provide sound evidence that homeopathic remedies are clinically different from placebos. However, the present analysis has several limitations that should be kept in mind when interpreting its conclusions. Even though a thorough search strategy was adopted, there is no absolute guarantee that all relevant articles were located."

      http//www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=9884175&dopt=Abstract - CONCLUSION The results of the available randomized trials suggest that individualized homeopathy has an effect over placebo. The evidence, however, is not convincing because of methodological shortcomings and inconsistencies. Future research should focus on replication of existing promising studies. New randomized studies should be preceded by pilot studies.

      And another good one http//www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=14960096&dopt=Citation - CONCLUSIONS Patients were very satisfied with their homeopathic treatment, both they and their physicians recorded significant improvement. Costs of homeopathic treatment were significantly lower than conventional treatment, and many previously prescribed drugs were discontinued.

      1 Reply Last reply
      0
      • I Offline
        I Offline
        ILisa
        wrote on last edited by
        #16

        I'm not going to go through a novel's worth of referencs, but anyway (these are not hand-picked, I just searched and clicked the first one each time)

        http//www.annals.org/cgi/reprint/138/5/393.pdf - Most clinical trials are poor. Most report no effect over placebos. Some report positive effects - but "further rigorous research is needed".

        Aw come on, OPF, Here's from the same article...

        DOES HOMEOPATHY WORK?
        The evidence for homeopathy?s effectiveness includes
        three areas of research 1) general comparisons of homeopathic
        remedies and placebos; 2) studies of homeopathy?s
        effectiveness for particular clinical conditions; and 3) studies
        looking for biological effects from potencies, especially
        the Homeopathic Remedy More Effective than
        Placebo?
        Four comprehensive, independent systematic reviews
        or meta-analyses have examined the question of whether
        homeopathic therapies behave like placebo in randomized,
        placebo-controlled trials (Table 2). These have comprehensively
        searched for all clinical trials and have used standard
        methods for quality evaluation and analysis of clinical
        trials. These reviews have found that, overall, the quality of
        clinical research in homeopathy is low. When only high quality
        studies have been selected for analysis (such as those
        with adequate randomization, blinding, sample size, and
        other methodologic criteria that limit bias), a surprising
        number show positive results. For example, Kleijnen and
        colleagues (2 did a detailed quality evaluation of 60 homeopathic
        clinical trials and concluded that they ?would
        be ready to accept that homeopathy can be efficacious, if
        only the mechanism of action were more plausible."homeopathy is more effective than placebo in general.

        CONCLUSIONS
        Homeopathy is an alternative therapeutic system based
        on the ?Principle of Similars? and the use of ?minimum?
        doses. Homeopathy was a prominent component of 19th century
        health care and recently has undergone a revival in
        the United States and around the world. Despite skepticism
        about the plausibility of homeopathy, some randomized,
        placebo-controlled trials and laboratory research report
        unexpected effects of homeopathic medicines.
        However, the evidence on the effectiveness of homeopathy
        for specific clinical conditions is scant, is of uneven quality,
        and is generally poorer quality than research done in allopathic
        medicine (61). More and better research is needed,
        Until homeopathy is better understood, it is important that physicians
        be open-minded about homeopathy?s possible value
        and maintain communication with patients who use it.

        I'm not going to go through all of the articles, this conversation is getting plain fruity. You see what you want to see, and I know from experience what I know. I will not abandon my homeopathic practice, regardless of what you say. I know what I know to be true, whether or not I can 'prove' it to you, jonny, and Randi.

        So, to take this thread back to the Glorious Reading, to you, your way of life, and to me mine. peace

        Good day!

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          unknownuser
          wrote on last edited by
          #17

          I don't doubt homeopathy. I just don't actually see how it could possibly work. Maybe it is actually a wonder drug, the FDA does suppress an aweful lot of things deeming them unscientific (cannabis plant, for instance).

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            ILisa
            wrote on last edited by
            #18

            I don't doubt homeopathy. I just don't actually see how it could possibly work. Maybe it is actually a wonder drug, the FDA does suppress an aweful lot of things deeming them unscientific (cannabis plant, for instance).

            Ahh............ salve to my wounds. handshake

            sun

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              jonny_k
              wrote on last edited by
              #19

              Peace "Ilisa",
              Ok so you showed the results. This is the first step but how do i know these results were done under proper control and/or not faked delberately or not properly controlled as was the case with Uri Geller at the Stanford Resreach Institution back in 1982? How would i know this? Ok wht i can do is send these results to JREF and see what they claim. GOD Bless!

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                jonny_k
                wrote on last edited by
                #20

                Peace "Ilisa",
                I sent your results to the JREF and this is what Randi replied

                You have selected meta-analyses. These depend entirely on how the data is selected. And they are indicative, not proof.

                We accept only original evidence.

                James Randi.

                GOD Bless!

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                  ILisa
                  wrote on last edited by
                  #21

                  Peace "Ilisa",
                  I sent your results to the JREF and this is what Randi replied
                  You have selected meta-analyses. These depend entirely on how the data is selected. And they are indicative, not proof.

                  We accept only original evidence.

                  James Randi.
                  GOD Bless!

                  Greetings jonny-k

                  Thanks! This is a step forward, at least now they are saying 'indicative'!!!

                  What do they mean by 'original evidence' ---that we have to do the research ourselves?? Or that we do something in front of them?

                  Seriously, there is a homepathic remedy that I have repeatedly seen make bumps from an accident go down in front of my eyes. If we could only find two volunteers....one to hit and the other to be hit somewhere (like the shin), we'll watch the bump start to come up, then I'll administer the remedy and we'll all watch it go down. Would that be 'original evidence' enough for the randi foundation?

                  I'm serious. No joking. Want to do it??

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                    unknownuser
                    wrote on last edited by
                    #22

                    Greetings jonny-k

                    Thanks! This is a step forward, at least now they are saying 'indicative'!!!

                    What do they mean by 'original evidence' ---that we have to do the research ourselves?? Or that we do something in front of them?

                    Seriously, there is a homepathic remedy that I have repeatedly seen make bumps from an accident go down in front of my eyes. If we could only find two volunteers....one to hit and the other to be hit somewhere (like the shin), we'll watch the bump start to come up, then I'll administer the remedy and we'll all watch it go down. Would that be 'original evidence' enough for the randi foundation?

                    I'm serious. No joking. Want to do it??

                    Do you realise you would need around 100+ people of all different shapes, sizes, ages, races, etc to carry that out with a hint of credibility?

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                      Angel
                      wrote on last edited by
                      #23

                      the FDA does suppress an aweful lot of things deeming them unscientific (cannabis plant, for instance).

                      what do they suppress?

                      and why?

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                        ILisa
                        wrote on last edited by
                        #24

                        Do you realise you would need around 100+ people of all different shapes, sizes, ages, races, etc to carry that out with a hint of credibility?

                        Why 100 if we do it in front of their cameras? However, they can choose who the people are and the number of participants. I don't care. It doesn't matter.

                        We can, indeed it with all the participants of their choosing even. (Actually it would take 200 then...one to kick and one to be kicked. Or you could have some device hit them --whatever it would take to give them a 'goose-egg' in a relatively harmless spot.)

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                          jonny_k
                          wrote on last edited by
                          #25

                          Peace "ilisa"

                          Seriously, there is a homepathic remedy that I have repeatedly seen make bumps from an accident go down in front of my eyes. If we could only find two volunteers....one to hit and the other to be hit somewhere (like the shin), we'll watch the bump start to come up, then I'll administer the remedy and we'll all watch it go down. Would that be 'original evidence' enough for the randi foundation?

                          I'm serious. No joking. Want to do it??

                          JK- Yes i think it would be but under controlled conditions meaning that the selected volunteers you choose would have to be agreed upon by Randi as well as you and some of the JREF members will see to it that the volunteers chosen are not magicians. Then there would also be scientists present there to watch the phenomena again which both you and Randi would agree upon. As for the eg you mentioned, do you mean that the bump would go down in a couple of minutes just before anyones eyes through your homeopathic remedy? If thts the case and itd be proven then Randi would surely provide you not only with million USD but youll be world famous amongst all skeptics. Would you like to write to the jref yourself (www.randi.org) or should i regarding this? GOD Bless!

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                            ILisa
                            wrote on last edited by
                            #26

                            Greetings jonny_k

                            You can watch it go down before your eyes in a matter of minutes. If you want, and we give the remedy immediately, no bump will form, but for the sake of proving a point, we could let the bump begin to form so that no one could tell us that the bump wasn't going to form any way.

                            What the heck, I'll write Randi.....but if I get the million, I'll give you a slice!! handshake

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                              ILisa
                              wrote on last edited by
                              #27

                              Greetings again jonny_k,

                              Just when it was starting to look like we were getting somewhere with this, I've just been to Randi's site and I was reading the terms for the JREF Million Dollar Challenge and I came up against this road block

                              "12. This offer is not open to any and all persons. Before being considered as an applicant, the person applying must satisfy two conditions First, he/she must have a ?media presence,? which means having been published, written about, or known to the media in regard to his/her claimed abilities or powers. This can be established by producing articles, videos, books, or other published material that specifically addresses the person?s abilities. Second, he/she must produce at least one signed document from an academic who has witnessed the powers or abilities of the person, and will validate that these powers or abilities have been verified."

                              I am not a 'media presence'. So, now what to do?

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                                unknownuser
                                wrote on last edited by
                                #28

                                Why 100 if we do it in front of their cameras? However, they can choose who the people are and the number of participants. I don't care. It doesn't matter.

                                We can, indeed it with all the participants of their choosing even. (Actually it would take 200 then...one to kick and one to be kicked. Or you could have some device hit them --whatever it would take to give them a 'goose-egg' in a relatively harmless spot.)

                                What I mean is that you need a broad number of people for testing. Most medicine trials take a significant amount of people from everywhere, 100 was just a random number. It may work for one person, but not all.

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                                  AlFajr
                                  wrote on last edited by
                                  #29

                                  What about giving 1 person two bumps? And then applying the remedy on one and leaving the other. That could be pretty indicative I think.

                                  Peace
                                  Al

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                                    jonny_k
                                    wrote on last edited by
                                    #30

                                    Peace "Ilisa",

                                    Greetings again jonny_k,

                                    Just when it was starting to look like we were getting somewhere with this, I've just been to Randi's site and I was reading the terms for the JREF Million Dollar Challenge and I came up against this road block

                                    "12. This offer is not open to any and all persons. Before being considered as an applicant, the person applying must satisfy two conditions First, he/she must have a ?media presence,? which means having been published, written about, or known to the media in regard to his/her claimed abilities or powers. This can be established by producing articles, videos, books, or other published material that specifically addresses the person?s abilities. Second, he/she must produce at least one signed document from an academic who has witnessed the powers or abilities of the person, and will validate that these powers or abilities have been verified."

                                    I am not a 'media presence'. So, now what to do?

                                    JK- Yeah i forgot to tell you that. Theyve changed the rules i beleive at the beginning of this year since too much people were applying without any significant results so Randi wanted to focus on the more famous people in order to expose them since theyr misleading many. But dont let that sacre you. Do write to the JREF and if they wont accept ask themwhether they have any smaller communities, related to them and whose testimonies they accept, in the US and whether you could perform ceratin preliminary tests thre first. once you pass those Randi will surely invite you to take the major test in his own presence. Good luck and GOD Bless! sun

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                                      ILisa
                                      wrote on last edited by
                                      #31

                                      Greetings jonny_k,

                                      Okay. Done. I'll let you know what comes of it....

                                      Thanks.

                                      Lisa

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                                        Angel
                                        wrote on last edited by
                                        #32

                                        deleted

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                                          ILisa
                                          wrote on last edited by
                                          #33

                                          .....I'm back. And this is what I got from JREF (Alison Smith to be exact)

                                          Lisa Newlin,

                                          Thank you for your interest in the James Randi Educational Foundation's Million Dollar Challenge.

                                          We do not allow any testing protocols that involve injury or risk to the volunteers. There is simply no way to control exactly how injured someone gets when you try to bruise them.

                                          I would not be surprised at all if Arnica Montana could reduce swelling in a patient. However, an herb is not the same thing as a homeopathic remedy. A homeopathic remedy is diluted to the point where you can honestly say that throwing seven molecules of the active ingredient in the ocean and then drinking some of the Pacific would be equally effective.

                                          If you are saying that a homeopathic remedy of Arnica Montana would reduce swelling, then I suggest you come up with other viable ways of testing that and apply.

                                          However, keep in mind that the testing is under time constraints. Whoever was using the remedy could not leave the sight of the testers after they had used it, and the amount of time we would ask volunteers to devote to the test would have to be reasonable.

                                          Thank you again for your interest,

                                          JREF Challenge Desk

                                          Doesn't seem that their biggest concern is proving whether homeopathy truly works or not, but rather finding a way to offer the Million Dollar Challenge, but not really! P

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